While the wedding takes center stage, the hospital remains in chaos due to a tragic car crash involving college students on their way to graduation.
In , the Season 5, Episode 22 milestone titled " What a Difference a Day Makes " is a landmark 100th episode that originally aired on May 7, 2009. It is widely celebrated for its emotional depth, shifting from a planned grand wedding for Meredith and Derek to a poignant ceremony for Izzie Stevens and Alex Karev. The Unexpected Wedding [S5E22] What a Difference a Day Makes
: Jeffrey Dean Morgan makes a final appearance as Denny Duquette, appearing as a hallucination to Izzie that Derek and Bailey eventually realize is a symptom of her worsening condition. Behind the Scenes Facts While the wedding takes center stage, the hospital
: After Derek and Bailey discover that Izzie has an inoperable brain tumor, the group decides to celebrate her life and love immediately. The Unexpected Wedding : Jeffrey Dean Morgan makes
While the wedding takes center stage, the hospital remains in chaos due to a tragic car crash involving college students on their way to graduation.
In , the Season 5, Episode 22 milestone titled " What a Difference a Day Makes " is a landmark 100th episode that originally aired on May 7, 2009. It is widely celebrated for its emotional depth, shifting from a planned grand wedding for Meredith and Derek to a poignant ceremony for Izzie Stevens and Alex Karev. The Unexpected Wedding
: Jeffrey Dean Morgan makes a final appearance as Denny Duquette, appearing as a hallucination to Izzie that Derek and Bailey eventually realize is a symptom of her worsening condition. Behind the Scenes Facts
: After Derek and Bailey discover that Izzie has an inoperable brain tumor, the group decides to celebrate her life and love immediately.