The term "subtype" has officially replaced "variant" for distinct morphologic categories. "Variant" is now reserved specifically for genomic alterations.
Several renal tumours are now defined by their genetic alterations, such as SMARCB1-deficient medullary renal cell carcinoma (RCC), TFEB-altered RCC, and ELOC-mutated RCC. Pathology and Genetics of Tumours of the Urinar...
WHO/ISUP grading is now recommended for all RCCs. For bladder tumours, any presence (even ≥is greater than or equal to The term "subtype" has officially replaced "variant" for
Muscle-invasive bladder carcinoma is now categorized into six molecular subgroups: luminal-papillary, luminal non-specified, luminal-unstable, stroma-rich, basal-squamous, and neuroendocrine-like. Pathology and Genetics of Tumours of the Urinar...