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Overview



Atrophy ●

Atrophy involves the wasting of tissues due to catabolic processes exceeding anabolic synthesis, commonly classified into disuse and neurogenic types in skeletal muscle, as well as cerebral atrophy in neurodegenerative conditions. Molecularly, this wasting is driven by ubiquitin-proteasome and autophagy-lysosome pathways, with emerging research focusing on the muscle-brain axis and the impact of cognitive offloading. For more detailed information, review the findings on NIH's PubMed Central at PMC .

This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more Cellular and molecular mechanisms of muscle atrophy - PMC



Modeling Reality



atrophy Modeling Nature and Physics is a growing practice for reaching true-to-life systems simulations with 'alive' feedbacks, including complexity management and unpredictability integration.

While in the past running an accurate Physical Modeling simulation was possible (due to its complexity) only on expensive multi-processor workstations or even computer clusters, today thanks to the exponential increase of modern CPUs' processing power, reaching parity with real instruments is possible in real-time (including polyphony and multi-istances possibilities) at a fraction of the costs.

IronAxe is the first in a series of instruments developed by Xhun Audio to use this revolutionary technology. The core of this kind of approach is the interaction between the Instrument's model, the Performer's model and the Unpredictability simulation.

All the six Strings, the Transducers (Pickups), the Plectrum/Finger excitation and more as well as Performer's actions like Palm Muting, Tapping Harmonics (even muting a String after its excitation is possible) are physically simulated. Add Unpredictability (instrument's and performances' micro-imperfections) to the equation and what you hear at the end of the whole process is given by the interaction of this three worlds.

The result is an 'alive' instrument, a state-of-the-art simulation for an unparalleled realism.


Features



Atrophy involves the wasting of tissues due to catabolic processes exceeding anabolic synthesis, commonly classified into disuse and neurogenic types in skeletal muscle, as well as cerebral atrophy in neurodegenerative conditions. Molecularly, this wasting is driven by ubiquitin-proteasome and autophagy-lysosome pathways, with emerging research focusing on the muscle-brain axis and the impact of cognitive offloading. For more detailed information, review the findings on NIH's PubMed Central at PMC .

This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more Cellular and molecular mechanisms of muscle atrophy - PMC



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IronAxe






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